Effects of Metabolic and Respiratory Acidosis & Alkalosis

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Respiratory acidosis and hypochloremic alkalosis: origins, differentiation, effects and therapy.

The combination of an increased serum total co2 content and lowered levels of serum chloride may result from a primary retention of co2 as in cardiopulmonary disease with a secondary lowering of the chloride level, referred to as respiratory acidosis, or it may represent one of the two forms of metabolic alkalosis, i.e., the hypochloremic type stemming from losses of extracellular chloride rath...

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Effects of metabolic alkalosis, metabolic acidosis and uraemia on whole-body intracellular pH in man.

1. Whole-body intracellular pH (pHi) was measured by the 14C-labelled DMO method in twenty-four control subjects, eighteen normal subjects with induced acute metabolic alkalosis, ten normal subjects with induced acute metabolic acidosis, twelve normal subjects with chronic acidosis and in fifteen patients with chronic renal insufficiency and acidosis. 2. The change in pHi per unit change in ext...

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Citrate metabolism in blood transfusions and its relationship due to metabolic alkalosis and respiratory acidosis.

Metabolic alkalosis commonly results from excessive hydrochloric acid (HCl), potassium (K(+)) and water (H2O) loss from the stomach or through the urine. The plasma anion gap increases in non-hypoproteinemic metabolic alkalosis due to an increased negative charge equivalent on albumin and the free ionized calcium (Ca(++)) content of plasma decreases. The mean citrate load in all patients was 87...

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The respiratory response to chronic metabolic alkalosis and acidosis in disease.

1. The respiratory response to chronic metabolic alkalosis was defined on the basis of 182 determinations of the arterial blood pH, Pco,, HCO,concentration and Po, obtained in thirty uraemic patients undergoing chronic haemodialysis. Plasma bicarbonate concentrations, [HC03 -1, ranged from 20 to 38 mmol/l before dialysis, and were elevated by increasing the acetate content of the dialysate. 2. ...

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Acidosis and Alkalosis

Price, Rs. 5-10. ^ t^e acj(i.base During recent years, the disturbance more -widely equilibrium in the body is being m causation of recognized as an important factor ?00(J deal of disease. Within the last 50 y?a? 5 g helped to throw research work has been done which ^ chemical light on this difficult physiolog eraiiy accepted problem. It has, for instance, Pe ? fj [n a state comthat for the org...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1974

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197404000-00760